Retrospective study of hepatic neoplasms in dogs (1999-2012)

Pinheiro Arrais Aloia, ThiagoViola Bosch, RosemarySoares Sanches, DanielLúcia Zaidan Dagli, MariaJavier Hernandez-Blazquez, FranciscoCogliati, Bruno

Primary hepatic neoplasms (PHN) account for 0.6 to 1.5% of canine tumours and constitute a major portion of chronic liver disease. The canine hepatic neoplasms can be classified as hepatocellular adenoma/carcinoma (HA/HCC), cholangiocellular adenoma/carcinoma (CCA/CCC), neuroendocrine carcinoma of tumors of mesenchymal origin, vascular or hematopoietic. Thus, because of its importance in veterinary oncology and hepatology, we performed a retrospective study of primary canine liver cancer in the Department of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, between 1999 and 2012. Was evaluated 6886 histopathological analysis, 106 (1.5%) were related to canine liver diseases, in which the tumors accounted for 27 cases (25.47%). Liver neoplasms, were classified as HA (2 cases -7.4%); CCA (5 cases - 18.5%); HCC (5 cases - 18.5%); CCC (6 cases - 22.2%) and 9 tumors of mesenchymal, hematopoietic or vascular (33.3%). Epidemiological data showed similarities to previously reported data, predominantly CCC, HCC and CCA in older animals and females.

1. epidemiology
2. vimentin
3. veterinary oncology
4. primary hepatic neoplasms
5. veterinary hepatology