Periódicos Brasileiros em Medicina Veterinária e Zootecnia

p. 31-36

COX-2 and TGF-ß expression in proliferative disorders of canine prostate

Marcela M.P. RodriguesGiovana W. Di SantisVeridiana M.B.D. de MouraRenée L. Amorim

COX-2 and TGF-_ expression was determined in order to correlate non-neoplastic lesions, preneoplastic lesions and carcinoma in the prostate of dogs. The results show that neoplastic and preneoplastic lesions express more COX-2 and TGF-_ when compared to carcinomas, which suggests these proteins may cooperate in the process of prostate tumorigenesis.(AU)

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