Mandibular squamous cell carcinoma in a captive Siberian tiger (Panthera tigris altaica)

Oliveira, Ayisa R. deCarvalho, Tatiane F. deArenales, AlexandreTinoco, Herlandes PCoelho, Carlyle MCosta, Maria Elvira L. TPaixão, Tatiane ACaixeta, Eduardo APinheiro, Guilherme R. GSantos, Renato L

Squamous cell carcinoma (SCC) is a common oral neoplasm in domestic cats, but there are only a few reports in wild felids. A captive 10-years-old, female Siberian tiger (Panthera tigris altaica), with history of chronic renal disease and serologically positive for Leishmania sp. developed a lytic mandibular nodule that was histologically diagnosed as SCC. At necropsy was also observed an exocrine pancreatic carcinoma, which was considered an incidental finding, and a chronic lympho-plasmocytic interstitial nephritis associated with a membranous glomerulopathy, compatible with the chronic renal disease presented by the animal. To the best of our knowledge this is the first report of an invasive and non-metastatic mandibular SCC in a Siberian tiger.(AU)

1. wild felid
2. leishmaniasis
3. SCC
4. pancreatic carcinoma
5. oral neoplasia