Drug resistance profiles and clonality of sporadic Shigella sonnei isolates in Ankara, Turkey

Kacmaz, BirgulUnaldi, OzlemSultan, NedimDurmaz, Riza

The aims of this study were to investigate drug resistance rates, types of extended spectrum beta lactamases (ESBLs), and molecular epidemiological characteristics of 43 Shigella sonnei isolates. Ampicillin-sulbactam, amoxicillin-clavulanate, chloramphenicol, and ciprofloxacin were the most active antibiotics. Five isolates harbored blaSHV-12, blaTEM-1 and blaCTX-M-15. More than 90% of the isolates had an indistinguishable pulsotype.

1. Pulsed-field gel electrophoresis
2. Plasmid profile
3. Extended spectrum beta-lactamase
4. Shigella sonnei