Canarypox virus expressing infectious bursal disease VP2 protein as immunogen for chickens

Zanetti, Flavia AdrianaGrand, María Daniela ConteMitarotonda, Romina CristinaTaboga, Oscar AlbertoCalamante, Gabriela

Canarypox viruses (CNPV) carrying the coding sequence of VP2 protein from infectious bursal disease virus (IBDV) were obtained. These viruses were able to express VP2 protein in vitro and to induce IBDV-neutralizing antibodies when inoculated in specific pathogen-free chickens demonstrating that CNPV platform is usefulness to develop immunogens for chickens.(AU)

1. canarypox virus
2. VP2 protein
3. IBDV
4. viral vector