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Periódicos Brasileiros em Medicina Veterinária e Zootecnia

Nitrate reductase assay using sodium nitrate for rapid detection of multidrug resistant tuberculosis

Bidart Macedo, MaíraVon Groll, AndreaFissette, KristaCarlos Palomino, JuanEduardo Almeida da Silva, PedroMartin, Anandi

We validated the nitrate reductase assay (NRA) for the detection of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) using sodium nitrate (NaNO3) in replacement of potassium nitrate (KNO3) as nitrate source. NaNO3 is cheaper than KNO3 and has no restriction on use which facilitates the implementation of NRA to detect MDR-TB.

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