Serum calprotectin levels in dogs with diarrhea
Simsek, AynurKochan, AkinAlp, Simten YesilmenIpek, Duygu Neval SayinIcen, Hasan
Background: Diarrhea induced by infectious factors may lead to significant health problems in dogs. Canine parvovirus(CPV), canine coronavirus (CCV), canine distemper virus (CDV), Giardia spp., Escherichia coli (E. coli), and Salmonella spp. are the important infectious agents that may induce diarrhea in dogs. The present study aimed to investigatethe effect of CPV, CCV, CDV, Giardia spp., E. coli, and Salmonella spp. infections on the change in serum calprotectin(Calp) concentration.Materials, Methods & Results: A total of 30 dogs were enrolled in the study. The study dogs were divided into 3 groups.Healthy animals as confirmed by clinical examination and animals negative for the specified pathogens were placed inGroup 1. Animals infected by one or more agents, including CPV, CCV, CDV, and Giardia spp., but negative for E. coli orSalmonella spp. were placed in Group 2. Finally, animals positive for E. coli or Salmonella spp. and infected or not infectedby one or more agents, including CPV, CCV, CDV, and Giardia spp., were placed in Group 3. Stool samples and rectaland conjunctival swab samples were collected to investigate the etiologic agents that induced diarrhea. Blood samples werecollected through vena cephalica antebrachii for hematological and biochemical examinations. The samples were obtainedvia routine clinical examinations at the Prof. Dr. Servet Sekin outpatient clinic at Dicle University Veterinary Faculty. CPV,CCV, CDV, and Giardia spp. diagnoses were made based on immunochromatographic test kits. The bacteriological analysisof stool samples was used to diagnose E. coli and Salmonella spp. infection...(AU)
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