Necrotic wound caused by jararaca (Bothrops jararaca) in a dog - hyperbaric oxygen therapy (HBTO)

Sakata, Stella Helena; Gallina, Marina Frazatti; Mizobe, Thamires; Pereira, Guilherme Cirino Coelho; Almeida, Karina Calixto de; Zadra, Vivian Ferreira; Cramer, Claudia Tozato; Santos, Ivan Felismino Charas dos

Necrotic wound caused by jararaca (Bothrops jararaca) in a dog - hyperbaric oxygen therapy (HBTO)

Sakata, Stella HelenaGallina, Marina FrazattiMizobe, ThamiresPereira, Guilherme Cirino CoelhoAlmeida, Karina Calixto deZadra, Vivian FerreiraCramer, Claudia TozatoSantos, Ivan Felismino Charas dos

Background: Snakebites are the main responsible for envenoming in dogs and the bothropic venom remains the mostcommon in Brazil, which can induce a necrotic skin wound. Hyperbaric oxygen therapy (HBOT) use 100% oxygen underhigh pressure and used to treat different wounds in human patients. To the authors knowledge, no reports regarding to usethe HBOT in skin wound caused by snakebite (Bothrops jararaca) are present in the literature. The present clinical caseaimed to describe the use of HBOT for the treatment of an extensive necrotic wound caused by jararaca snakebite in a dog.Case: A neutered 8-year-old mixed-breed dog, weighing 12 kg, was admitted with a 7-day history of extensive necroticwound was identified in the face and neck causing by a snakebite, and no sign of pain. The procedure of HBOT (singlesessions of 1.5 ATM, 45 min, repeated every 48 h, up to 12 sessions) was decided, and the complete blood cells, alanineaminotransferase, creatinine, creatine kinase, prothrombin time, activated partial thromboplastin time, wound clinicalevaluation were measured at the following time-points: 2nd, 5th, 10th, and 12th sessions. At the 5th session was identifiedleukopenia, neutropenia and lymphopenia. Wound re-epithelialization was initiated after the 5th session, and the completeepithelialization was identified at the 12th session of HBOT. During the HBOT no side effects were identified. Threemonths after the HBOT finished, the animal returned to the clinic and the clinical status evolved positively, and the woundwas completed healed.Discussion: This report described the treatment of an extensive necrotic skin wound caused by snakebite (Bothrops jararaca)in an 8-year-old, neutered, mixed-breed dog using the HBOT. The wound healing...(AU)