Comparison of the effects of maropitant, lidocaine, and dextroketamine administered by the intratesticular route in dogs undergoing elective orchiectomy

Gomes, Lianna Ghisi; Dower, Nathalie Moro Bassil; Stocco, Matias Bassinello; Martini, Andresa de Cássia; Ferreira, Camila Calvi Menegassi; Oliveira, Anderson Castro Soares de; Flôres, Fabíola Niederauer; Souza, Roberto Lopes de; Guimarães, Luciana Dambrósio

Comparison of the effects of maropitant, lidocaine, and dextroketamine administered by the intratesticular route in dogs undergoing elective orchiectomy

Gomes, Lianna GhisiDower, Nathalie Moro BassilStocco, Matias BassinelloMartini, Andresa de CássiaFerreira, Camila Calvi MenegassiOliveira, Anderson Castro Soares deFlôres, Fabíola NiederauerSouza, Roberto Lopes deGuimarães, Luciana Dambrósio

Background: Balanced anesthesia achieved with combinations of inhaled and injectable drugs administered systemicallyor in loco-regional anesthetic blocks, is widely used in veterinary medicine. The use of anesthesia and/or local analgesiahas already demonstrated benefits in the performance of elective orchiectomy in different species, there is no literature thatevaluates the use of the maropitant intratesticular route. The present study evaluated the cardiorespiratory variables andanalgesia produced by intratesticular blockade with maropitant, lidocaine, or dextroketamine during the trans-operativeperiod along with the discharge and anesthetic recovery of dogs that underwent elective orchiectomy.Materials, Methods & Results: Used twenty-four dogs from routine elective orchiectomy, considered healthy based onthe results of clinical and hematological tests. The animals were randomly divided into three groups and was applied intratesticularly 2% lidocaine at a dose of 1 mg/kg (GL), 5% dextrocetamina at a dose of 2.5 mg/kg (GC), or 1% maropitantat a dose of 1 mg/kg (GM). Anesthesia induction was performed with propofol (to effect), and stabilization of inhalationalanesthesia was achieved with 1.7 V% of sevoflurane diluted in 100% oxygen administered through a calibrated vaporizerand appropriate anesthetic system based on the animals weight, being kept under spontaneous ventilation, After induction, we waited 10 min for stabilization of exhaled anesthetic concentration and then administered one of the treatmentsintratesticularly. After five min from the local block the surgical procedure was started during up to 15 min. Heart rate(HR), respiratory rate (RR), systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure(MAP), oxygen saturation of hemoglobin (SatO2), end-tidal carbon dioxide partial pressure (EtCO2), end-tidal sevofluraneconcentration...(AU)