Periódicos Brasileiros em Medicina Veterinária e Zootecnia

Antimicrobial resistance and extended-spectrum beta-lactamase production in Enterobacteriaceae isolates from household cats (Felis silvestris catus)

Andrade, Ana Claudia SouzaSantos, Isabela Carvalho dosBarbosa, Lidiane NunesCaetano, Isabel Cristina da SilvaZaniolo, Melissa MarchiFonseca, Bianca DiasMartins, Lisiane de AlmeidaGonçalves, Daniela Dib

Background: In Brazil, cats in households has recently increased dramatically, likely due to their lower space and carerequirements. We need to know the health of these companion animal species, since they have behavioral patterns thatmake them an important link in the epidemiological chain. Extended spectrum beta-lactamase producer strains (ESBL)are resistant to penicillin, cephalosporin and monobactam, but they are susceptible to clavulanate. The goal of this study isto detect Enterobacteriaceae that produce extended spectrum beta-lactamase (ESBL) and evaluate the bacterial resistanceprofile in isolated cats (Felis silvestris catus) that live in a city located at west of Parana state, Brazil.Materials, Methods & Results: Swabs were aseptically collected from the anal orifice and oral cavity of 49 female domestic cats that were healthy upon clinical and physical examination, a minimum age of one year, weighing up to 3 kg,and had attended a veterinary clinic specializing in cats, in order to, later, perform the isolation and bacterial identification, antimicrobial sensibility phenotypic test and the phenotypic test to detect ESBL producer strains. From the 98 swabscollected it was possible to perform the bacterial isolation in 68 samples; 40.81% isolated from anal orifice and 28.57%isolated from oral cavity. From rectal and oral cavities 77.50% and 71.42% of the isolated were identified as Escherichiacoli respectively, being 2.94% considered ESBL producer strains. In relation to bacterial resistance the antibiotics thatshown more resistance in anal orifice were ampicillin, amoxicillin, nalidixic acid, sulfazotrim, tetracycline and aztreonam.In oral cavity they were ampicillin, amoxicillin, cefoxitin, amoxicillin + clavulanate, aztreonam, ceftriaxone and nalidixicacid; and the bacterial resistance index shown that 39.70% were considered high level risk...(AU)

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