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Periódicos Brasileiros em Medicina Veterinária e Zootecnia

Pacientes com carcinoma de células escamosas - relação do tratamento com o prognóstico

Tillmann, Mariana TeixeiraFelix, Anelize de Oliveira CampelloFernandes, Cristina GevehrCapella, Sabrina de OliveiraMueller, Eduardo NegriNobre, Márcia de Oliveira

Background: Squamous cell carcinoma (SCC) is a malignant cutaneous neoplasm which occurs frequently in small animals. Histopathology or fine needle aspiration cytology is necessary to confirm diagnosis; macroscopic diagnosis is not possible since the lesions are very similar to others of distinct etiologies. Owing to the fact that it is a neoplasm, diagnosis and treatment are usually not well accepted by owners, especially since it can cause esthetic changes to the animal and adjunct treatments can cause unwanted side effects. The objective of this study was to report clinical cases of SCC with distinct tumor subtypes and relate the recommended treatment with prognosis of patients. Case: Two dogs and one cat with SCC that were subjected to physical and dermatological examination, and tested negative for sporotrichosis, cryptococcosis, and manges. Dog 1 (male, 9-year-old, yellow Labrador retriever) exhibited inspiratory dyspnea for three weeks owing to an ulcerative hemorrhagic lesion on the nose. In view of the site of the lesion, a radiographic exam was requested, and the bony portion of the septum was found to be compromised. Cat 2 (female, 10-year-old, bicolor, mixed-breed cat) exhibited a focal, punctate, ulcerated, hemorrhagic lesion on the nose. Dog 3 (female, 10-year-old, white Dogo Argentino) exhibited several ulcerative lesions, and papulae, plaques and comedones on the ventral region of the abdomen.Treatment for deep pyoderma and comedone syndrome were initially instituted; on follow-up, more ulcerative lesions were present, which prompted the inclusion of neoplasm as a differential diagnosis. In cases 1 and 3, histopathology was performed with diagnosis of undifferentiated and differentiated SCC, respectively. In both cases, surgical margins were compromised after resection of the lesion...(AU)

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