Evaluation of Two Protocols for Analgesia during Total Unilateral Mastectomy in Bitches
Eberhardt Assumpção, AndersonNaspolini, BárbaraSantalucia, SérgioCaroline Heymanns, AnaPaula Piovezan, Anna
Background: Proper evaluation of pain is essential to select effective anesthetic protocols in surgical procedures in animals. Pain assessment can be accomplished during the perioperative period by measuring several physiological parameters, such as heart and respiratory rates. Measuring serum levels of cortisol and glucose is one of the most commonly used methods to assess the effectiveness of protocols for pain control. The aim of this study was to compare two analgesic protocols in dogs undergoing unilateral total mastectomy, a surgery that can cause moderate-to-severe pain in dogs. Materials, Methods & Results: Eighteen female dogs seen at the Veterinary Hospital of the University of Southern Santa Catarina, Brazil, were recruited for this study, without stratification by breed and age, except for brachycephalic breeds. The animals were divided into two groups: 1) FLK group, in which the animals received preoperative ketamine (5 mg/ kg, IM) and midazolam (0.3 mg/kg, IM), an IV bolus of fentanyl (0.004 mg/kg), lidocaine (2 mg/kg) and ketamine (0.5 mg/kg), and then a combination of fentanyl (0.008 mg/kg/h), ketamine (0.6 mg/kg/h) and lidocaine (2 mg/kg/h) diluted in normal saline solution were infused at a rate of 10 mL/kg/h until the end of the surgical procedure; 2) AM group, in which the animals received preoperative morphine (0.5 mg/kg, IM) and acepromazine (0.05 mg/k
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