Osteossarcoma osteoblástico nasal em um bovino Wagyu
Santos, Alex dosDazzi, Cláudia CeruttiMachado, Tanise PolicarpoZanella, Eraldo LourensoZanella, RicardoCosta, Marcio MachadoRodriguez, RubensMotta, Adriana Costa da
Background: Osteosarcoma is a malignant mesenchymal tumor with a wide variety of histological patterns. It is the primary bone neoplasia diagnosed in most domestic animal clinic, but rare in farm animals. The tumor develops both the appendicular skeleton as the axial skeleton, the latter being less affected. Generally it has a fast, painful and infiltrative grow, being observed metastasis. This study aims to report a case of metastatic osteoblastic osteosarcoma in the nasal bone of a bovine, diagnosed at the Animal Pathology Laboratory at the University of Passo Fundo (UPF), featuring its pathological and immunohistochemical aspects. Case: A 5 year old Wagyu female beef cattle, was treated at the Veterinary Hospital of the University of Passo Fundo. The animal had swelling in the left nasal plan, dyspnoea and anorexia. It was held cytology and biopsy which revealed malignant mesenchymal neoplasm compatible with osteosarcoma. The clinical picture has worsened and the animal died. At necropsy, the left nasal plane, had ulcerated tumor mass measuring 15x12.5x7.5 cm, hard and firm consistency with whitish color that seeped up to the turbinates and sinuses. In the lung, there were numerous nodules of tumor appearance, adhered to the parietal pleura, similar to bone tissue. In the histopathological analysis, proliferation of neoplastic cells located in the deep dermis was observed [...](AU)
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