Periódicos Brasileiros em Medicina Veterinária e Zootecnia

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Effect of exogenous progesterone on success of ovsynch protocol in dairy cows with ovarian cyst

Yilmaz, OktayOzenc, Erhan Ahmet Ahmet

Background: It has been suggested that unresponsiveness of the hypothalamus to increasing estradiol may be an underlying mechanism in the development of ovarian cysts which may be treated with progesterone. Therefore, this study was designed to compare the effectiveness of Ovsynch and Ovsynch modifi ed with progesterone releasing intravaginal device (PRID) for the treatment of ovarian cysts that cause important economic in Holstein dairy cows.Materials, Methods & Results: Cows with ovarian cysts (n = 33) were divided into randomly Ovsynch (Ov) (n = 9) and Modifi ed Ovsynch (MOv) (n = 9) groups for follicular cysts and Ov (n = 7) and MOv (n = 8) groups for luteal cyst. Ov group were treated with im GnRH on Day 0, im PGF2 on Day 7, im GnRH on Day 9 and then were time-inseminated 18 h later. MOv group were treated with Ov protocol combined with PRID from Day 0 to 7. Data obtained by transrectal ultrasonography on Day 0, 7, 10, 17, 31 and 45 and progesterone (P4) and 17-estradiole (E2) concentrations in blood samples collected on Day 0, 7, 10, 17 and 31 were evaluated. The treatments resulted in regression, increased diameter or no changes in ultrasonic appearance in OV group in 2 (22%), 5 (56%) and 2 (22%) cows with follicular cyst and in 4 (57%), 2 (29%) and 1 (14%) cows with luteal cyst, respectively. MOv group showed regression, increased diameter or no changes in ultraso

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