Periódicos Brasileiros em Medicina Veterinária e Zootecnia

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A clinical trial and oral wound treated by essential oil of Lippia sidoides mouthrinse in horses

Gomes de Alencar-Araripe, MarcioCélia Sousa Nunes-Pinheiro, DianaOdebrecht Costa, BehatrizSampaio Batista, LidiaSilva Feitosa, MatheusKarlo Gama de Almeida, Gianda Rocha Tomé, AdrianaCarneiro Girão, Virgínia

Background: Frequently the equine oral cavity is target of dental alterations, irregular wear of the dentition, tartar accumulation, gums inflammation, and other oral mucosa lesions. Therapeutically, active plants have been proposed to act preventively against oral infections. The objective of this study was to evaluate a mouthrinse prepared with Lippia sidoides Cham. essential oil in equine dental diseases and oral wound healing treatment.Materials, Methods & Results: The experimental protocol was approved by the Ethics Committee of the Use of Animals (CEUA) of the State University of Ceara (UECE), n 1158255-0/75. Mouthrinse was prepared with essential oil extracted from leaves of L. sidoides (EOLS). Thymol was the main constituent of the oil, up to 70%. Horses were chosen based on clinical and oral examination. Dental calculus and gingivitis grade from incisor and canine teeth were scored during evaluation. Two groups were used; OELS group (n = 10), and control group (n = 6), treated with mouthwash without EO (MR). A surgical scar (0.5 x 2 cm) was made near tooth 106 with the animals sedated. The lesions were observed on days 0 (D0), 3 (D3), 7 (D7), and 14 (D14) after treatment that was applied once in 48 h for 14 days. Recovery of oral mucosa was, blindly, evaluated in tissue samples. EOLS treatment reduced teeth calculus scores from D0 to D14 (P 0.05). In relation to

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