Periódicos Brasileiros em Medicina Veterinária e Zootecnia

p. 01-05

Leucemia linfoblástica aguda em um cão

Loreno Raulino Tomaz, KlivioMenezes do Vale, AndréSoto-Blanco, Benito

Background: Leukemias are malign neoplasias of the hematopoietic precursor cells from the bone marrow. These neoplastic cells may or may not reach the blood circulation. Leukemias are classifi ed as lymphoid or myeloid depending on the leukocyte cell lineage affected. In addition, leukemias are classifi ed as either acute or chronic based on their cellular differentiation and proliferative aggressiveness. The leukemias from lymphoid cells that affect dogs include acute lymphoblastic leukemia and chronic lymphocytic leukemia. This paper describes the clinical and laboratorial fi ndings of a case of acute lymphoblastic leukemia in a female dog.Case: A seven-year-old female mixed-breed dog was referred to the Veterinary Hospital of the Universidade Federal Rural do Semi-Árido (UFERSA), Mossoró, State of Rio Grande do Norte, Brazil, for apathy, anorexia, weakness and weight loss. The clinical examination confirmed the apathy and weakness. The mucous membranes were pale, the body temperature was 40.5C, the heart rate was 120 bpm, the capillary refi ll time was 2 s, and no abnormalities were found on auscultation. Diagnostic laboratory tests were completed, including a serum test for canine leishmaniasis, a serum biochemistry panel, a complete blood cell count, and a bone marrow analysis. The canine leishmaniasis serology (enzyme-linked immunosorbent assay and indirect fl uorescent-

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