Periódicos Brasileiros em Medicina Veterinária e Zootecnia

p. 01-04

Edema maligno em equino causado por Clostridium chauvoei

Targino Silva Almeida e Macêdo, JulianaSadanã Pires, PrhiscyllaEmydio Gomes Pinheiro, EmmanuelSantana de Oliveira, RicardoOtávio Silveira Silva, RodrigoCarlos Faria Lobato, FranciscoMiguel Ocampos Pedroso, Pedro

Background: Malignant edema occurs when a wound is contaminated by one or a combination of the following bacteria: Clostridium septicum, C. sordellii, C. chauvoei, C. novyi type A, and C. perfringens type A. Although malignant edema has been recognized as a disease of economic importance in domestic ruminants, it has rarely been reported in horses in Brazil. Immunohistochemistry is a method that combines histological, immunological and biochemical techniques which, with the use of specifi c antibodies, detects the agent in situ. This paper reports a case of malignant edema by Clostridium chauvoei in a horse in Bahia, Brazil.Case: A 4.5-year-old male horse was submitted for necropsy. The clinical history was obtained from the owner. Samples from the abdominal cavity, thoracic cavity, central nervous system and integumentary system were collected. The samples were fi xed in 10% formalin, processed routinely for histology, embedded in paraffi n, sectioned at fi ve microns, and stained with hematoxylin and eosin. Additionally, histological sections were subjected to immunohistochemistry anti-Clostridium perfringens type A, C. septicum, C. chauvoei, C. novyi type A, and C. sordellii. Positive and negative controls were included. The animal presented diffi culty in walking, swelling of the pelvic limbs two days after intramuscular anti-infl ammatory treatment, and died seven hours af

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