Periódicos Brasileiros em Medicina Veterinária e Zootecnia

p. 01-04

Diabetes insípido em um cão

riliaariliaariliaariliade Pietro, AlessandraBrolo Martins, Danieli

Background: Diabetes insipidus (DI) is a rare endocrine disorder in dogs altering the mechanism of retention and excretion of water, with concomitant polyuria and polydipsia (PU/PD), and low urine specifi c gravity. The water deprivation test followed by response to application of desmopressin is the diagnostic test for the disease. However, the literature is still scarce about laboratorial and clinical aspects of DI in small animals. Thus, the aim of this study is to report a case of DI in a canine, emphasizing its diagnosis through the water deprivation test.Case: A male mongrel dog, 5 years-old, not neutered, 13kg of body weight, was presented with intense PU/PD (500mL/kg/day of water consumption). Physical examination showed normal routine clinical parameters. Additional tests were asked (abdominal ultrasound, blood count, serum biochemical (creatinine, alanine aminotransferase (ALT), total cholesterol, alkaline phosphatase (ALP) and glucose) and dexamethasone suppression test), but they showed no signifi cant changes. Thus, it was suspected that the animal had an uncommon endocrinopathy, DI. For its confi rmation, it was made the water deprivation test with application of desmopressin acetate. The patient remained without access to water and without fluidtherapy with urethral sounding and bladder emptying. The measurement of urinary gravity and volume were made every hour

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