Periódicos Brasileiros em Medicina Veterinária e Zootecnia

p. 01-12

Metabolismo de biomoléculas na embriogênese do carrapato Rhipicephalus (Boophilus) microplus

Garcia Guizzo, MelinaAbreu, LeonardoMasuda, AoiLogullo, Carlosda Silva Vaz Junior, Itabajara

Background: The hard tick Rhipicephalus (Boophilus) microplus is an hematophagous ectoparasite that causes important economic losses in the cattle raising. The control of the parasite is usually accomplished through the use of acaricides. Even though these chemicals substances present effectiveness, their continuous use can lead to the selection of resistant parasites. When not used properly acaricides can cause environmental damages in addition to risks for animal and human health. Because of these drawbacks there are efforts to the development of alternatives control methods. The immunological control is a promissing method due to target specifi city, which increases the environmental and animal safety. The development of such approach relies on the discovery and characterization of molecules involved in the metabolism of the parasite different life stages. The embryogenesis is the stage where the metabolites of maternal origin are mobilized through catabolic and anabolic pathways necessary for the development of the embryo. The study of the substrates and enzymes involved in metabolic pathways of the embryogenesis allows the directed search to potential antigens to the development of an anti-R. microplus vaccine.Review: The embryo, during its development, passes through the stages of a sincicial blastoderm, celular blastoderm and segmentation, and both morfological changes a

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