Description of a new experimental model skin flap for studying skin viability in rats

Camargo, Cristina PiresMargarido, Nelson FontanaGuandelini, EduardoVieira, Guilherme Alexandre BarrucciJacomo, Alfredo LuizGemperli, Rolf

To describe a new experimental flap for studying skin viability in rats. METHODS: Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups. RESULTS: Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001). CONCLUSION: The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability.(AU)

1. Models, Animal
2. Necrosis
3. Surgical Flaps
4. Rats